Prescription Drugs

The non-medical use or abuse of prescription drugs remains a serious public health concern. According to the National Institute on Drug Abuse's (NIDA) research report Prescription Drugs: Abuse and Addiction, there are three classes of prescription drugs that are most commonly abused: opioids, which are most often prescribed to treat pain-examples include: codeine, oxycodone (OxyContin and Percocet), and morphine (Kadian and Avinza);

  • central nervous system (CNS) depressants, which are used to treat anxiety and sleep disorders-examples include: barbiturates (Mebaral and Nembutal) and benzodiazepines (Valium and Xanax);
  • stimulants, which are prescribed to treat the sleep disorder narcolepsy, attention-deficit hyperactivity disorder (ADHD), and obesity-examples include: dextroamphetamine (Dexedrine and Adderall) and methylphenidate (Ritalin and Concerta).

Many Americans benefit from the appropriate use of prescription pain killers, but, when abused, they can be as addictive and dangerous as illegal drugs. Prescription drugs should only be taken exactly as directed by a medical professional.

The Synthetic Drug Control Strategy addresses the extent of and problems associated with prescription drug abuse. Prescription drugs account for the second most commonly abused category of drugs, behind marijuana and ahead of cocaine, heroin, methamphetamine, and other drugs. Prescription drug abuse poses a unique challenge because of the need to balance prevention, education, and enforcement, with the need for legitimate access to controlled substance prescription drugs.

Health Effects

The health risks associated with prescription drug abuse vary depending on the drug. For example, abuse of opioids, narcotics and pain relievers can slow or stop breathing. The abuse of depressants, including benzodiazepines and other tranquilizers, barbiturates and other sedatives, can result in seizure, respiratory depression and decreased heart rate. Stimulant abuse can lead to high body temperature, irregular heart rate, cardiovascular system failure and seizure. Inappropriate use of prescription drugs, including use without a prescription or medical supervision, or using in a manner other than exactly as prescribed, can lead to addiction in some cases.

The Drug Abuse Warning Network (DAWN) receives reports of emergency department (ED) episodes involving the non-medical use of legal drugs. These can involve the deliberate abuse of prescribed or legally obtained over-the-counter (OTC) medications or of pharmaceuticals diverted for abuse. Accidental overdoses or adverse reactions to OTC or prescription drugs taken as directed are not reportable to DAWN unless they are present in combination with an illicit drug.
For further information on the White House Drug Policy go to

For further Information from The White House Drug Policy go to  www.whitehousedrugpolicy.gov

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