HALLUCINOGENSHallucinogenic substances are characterized by their ability to cause changes in a person's perception of reality. Persons using hallucinogenic drugs often report seeing images, hearing sounds, and feeling sensations that seem real, but do not exist. In the past, plants and fungi that contained hallucinogenic substances were abused. Currently, these hallucinogenic substances are produced synthetically to provide a higher potency. LSD (lysergic acid diethylamide) is one of the major drugs making up the hallucinogen class of drugs. It was discovered in 1938 and is manufactured from lysergic acid, which is found in ergot, a fungus that grows on rye and other grains. PCP (phencyclidine) was developed in the 1950s as an intravenous anesthetic, but its use in humans was discontinued in 1965, because patients often became agitated, delusional, and irrational while recovering from its anesthetic effects. PCP is now being illegally manufactured in laboratories. It is a white crystalline powder that is readily soluble in water or alcohol. It has a distinctive bitter chemical taste. PCP can be mixed easily with dyes and turns up on the illicit drug market in a variety of tablets, capsules, and colored powders. It can be snorted, smoked, or ingested. For smoking, PCP is often applied to a leafy material such as mint, parsley, oregano, or marijuana. Psilocybin is obtained from certain mushrooms found in South America, Mexico, and the U.S, although the substance can also be produced synthetically. Mushrooms containing psilocybin are available fresh or dried with long, narrow stems topped by caps with dark gills on the underside. These mushrooms are usually ingested orally, but can also be brewed in a tea or added to food to mask the bitter flavor. Once ingested, psilocybin is broken down in the user's body to produce psilocyn, another hallucinogenic substance. Dextromethorphan (sometimes called "DXM" or "robo") is a cough-suppressing ingredient in a variety of over-the-counter cold and cough medications. At the doses recommended for treating coughs, the drug is safe and effective. At much higher doses, dextromethorphan produces dissociative effects similar to those of PCP and ketamine. Health Effects Hallucinogens can produce physiological effects including elevated heart rate, increased blood pressure, and dilated pupils. These drugs are often unpredictable and a user may experience different effects compared to other users or past usage. Users often experience changes in perception, thought, and mood. The effects of LSD are unpredictable. They depend on the amount of the drug taken; the user's personality, mood, and expectations; and the surroundings in which the drug is used. Usually, the user feels the first effects of the drug within 30 to 90 minutes of ingestion. These experiences last for extended periods of time and typically begin to clear after about 12 hours. The physical effects include dilated pupils, higher body temperature, increased heart rate and blood pressure, sweating, loss of appetite, sleeplessness, dry mouth, and tremors. Sensations may seem to "cross over" for the user, giving the feeling of hearing colors and seeing sounds. If taken in a large enough dose, the drug produces delusions and visual hallucinations. The effects of PCP use are unpredictable, can be felt within minutes of ingestion, and can last for many hours. Physical effects can include shallow, rapid breathing; increased blood pressure; elevated heart rate; and increased temperature. Nausea, blurred vision, dizziness, and decreased awareness can also occur. High doses of PCP can cause convulsions, coma, hyperthermia, and death. PCP is an addictive drug that can cause psychological dependence, cravings, and compulsive drug seeking behaviors. Physical effects of psilocybin are usually experienced within 20 minutes of ingestion and can last for 6 hours. Negative physical symptoms of psilocybin use can include vomiting, muscle weakness, drowsiness, and panic reactions. Frequent use of this drug can result in the development of a tolerance. For further Information from The White House Drug Policy go to www.whitehousedrugpolicy.gov |
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